Erdheim Chester Disease Definition

Erdheim chester disease ecd is a rare non langerhans histiocytic disorder most commonly characterized by multifocal osteosclerotic lesions of the long bones demonstrating sheets of foamy histiocytes on biopsy with or without histiocytic infiltration of extraskeletal tissues. Erdheim chester disease ecd is a rare multisystem disorder of adulthood. The symptoms can range from mild to severe and life threatening.

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Erdheim chester disease is a rare form of non langerhans cell histiocytosis.

Erdheim chester disease definition. It was declared a histiocytic neoplasm by the world health organization in 2016. The primary characteristic of erdheim chester disease is the accumulation of histiocytes in multiple tissues and organs of the body. These cells which normally help fight infection and injury then gather in different organs and tissues and can result in a variety of symptoms including organ failure. Erdheim chester disease is most common in adults.

Histiocytes are large phagocytic cells macrophages that normally play a role in responding to infection and injury. Ecd causes the over production of immune cells called histiocytes which then accumulate in tissues and organs in the body. It is characterized by excessive production and accumulation of histiocytes within multiple tissues and organs. It involves the excessive production of histiocytes which are a type of white blood cell.

Erdheim chester disease is a rare type of slow growing blood cancer called a histiocytic neoplasm which results in overproduction of cells called histiocytes. Histiocytes normally function to destroy foreign substances and protect the body from infection. Erdheim chester disease ecd is a rare condition that can affect many parts of the body. These cells which are called histiocytes infiltrate the loose connective tissue of the body.

Erdheim chester disease is an extremely rare pathological condition affecting multiple systems of the body which usually strikes in adulthood. It is characterized by excessive production and accumulation of specific cells whose normal function is to fight infections. Erdheim chester disease is a systemic histiocytic disorder diagnosed on the basis of a characteristic pattern of symmetric intramedullary sclerosis of long bones. It has been diagnosed in children but it most commonly affects adults.

Erdheim chester disease is a rare disease characterized by the abnormal multiplication of a specific type of white blood cells called histiocytes or tissue macrophages technically this disease is termed a non langerhans cell histiocytosis. Erdheim chester disease most often affects the long bones of the arms and legs but it can also affect the skin lungs heart kidneys brain tissue behind the eyes and the retroperitoneum the back wall of the abdomen. Erdheim chester disease is an extremely rare disorder that can affect many different organs of the body.